Location: Home>> Staff>> Home Page of Zihua Wang  
 
     
    Lihua Wang  
 
    Institute of Chemistry, Chinese Academy of Sciences, Bei Yi Jie 2, Zhong Guan Cun, 100190, Beijing
Tel: (010) 82362540，Email: wangzh[at]iccas.ac.cn		  
 
         Research  
      Zihua Wang joined Prof. Mingyuan Gao's group in July 2017, and his major research focuses on synthesis peptide functionalized nanomaterials and its biomedical applications.  
 
         Curriculum Vitae  
      May 1985             Born in Gansu Province  
      2004-2008            Bachelor degree, College of Life Sciences, Long Dong University  
      2008-2011            Master degree, College of Life Science, Shihezi University  
      2012-2014            Research assistant, National Center for Nanoscience and Technology  
      2014-2017            Ph.D., National Center for Nanoscience and Technology, CAS  
      2017.07-              Assistant Professor, Institute of Chemistry, CAS  
 
         Publication  
   
  1. Upconversion Luminescence Mediated Photodynamic Therapy through Hydrophilically Engineered Porphyrin
    Xiaodan Sun‡, Peisen Zhang‡, Yi Houa*, Yingying Li, Xiaodan Huang, Zihua Wang, Lihong Jing*, and Mingyuan Gao*
    Chem. Eng. Process, 2019, just accepted.
  2. Coordinatively Unsaturated Fe3+ Based Activable Probes for Enhanced MRI and Therapy of Tumors
    Peisen Zhang, Yi Hou*, Jianfeng Zeng, Yingying Li, Zihua Wang, Ran Zhu, Tiancong Ma, and Mingyuan Gao*
    Angew. Chem. Int. Ed., 2019, DOI: 10.1002/anie.201904880.
  3. ‘Smart’ Nanoprobes for Visualization of Tumor Microenvironment
    Tiancong Ma, Peisen Zhang, Yi Hou*, Haoran Ning, Zihua Wang, Jiayi Huang, and Mingyuan Gao
    Adv. Health. Mater., 2018, accepted.
  4. Identifying EGFR-Expressed Cells and Detecting EGFR Multi-Mutations at Single-Cell Level by Microfluidic Chip
    Ren Li, Mingxing Zhou, Jine Li, Zihua Wang, Weikai Zhang, Chunyan Yue, Yan Ma, Hailin Peng, Zewen Wei, Zhiyuan Hu*
    Nano-Micro Lett. 2018, DOI:10.1007/s40820-017-0168-y.
  5. Precisely Enumerating Circulating Tumor Cells Utilizing a Multi-Functional Microfluidic Chip and Unique Image Interpretation Algorithm
    Mingxing Zhou, Hui Zheng, Zhaoba Wang, Ren Li, Xiaoran Liu, Weikai Zhang, Zihua Wang,
    Huiping Li, Zewen Wei, Zhiyuan Hu*
    Theranostics 2017, 7(19): 4710-4721.
  6. Peptide probes Derived from Pertuzumab by Molecular dynamics Modeling for HER2 Positive Tumor Imaging
    Xiaoliang Yang, Zihua Wang, Zhichu Xiang, Dan Li, Zhiyuan Hu,Wei Cui, Lingling Geng, Qiaojun Fang*
    PLoS Comput. Biol. 2017, 13(4): e1005441.
  7. Tumor detection using Magnetosome Nanoparticles Functionalized with a newly Screened EGFR/HER2 Targeting Peptide
    Zhichu Xiang, Xiaoliang Yang, Junjie Xu, Wenjia Lai, Zihua Wang, Zhiyuan Hu*, Jiesheng Tian, Lingling Geng, Qiaojun Fang*
    Biomaterials 2017, 115, 53-64.
  8. PECT/CT Imaging of the Novel HER2-targeted Peptide Probe 99mTc-HYNIC-H6F in Breast Cancer Mouse Models
    Liqiang Li, Yue Wu, Zihua Wang, Bing Jia, Zhiyuan Hu, Chengyan Dong, and Fan Wang*
    J. Nucl. Med. 2017, 58(5):821-826.
  9. Targeting Peptide Functionalized Liposomes towards Aminopeptidase N for Precise Tumor Diagnosis and Therapy
    Xiangqian Jia, Qiuju Han, Zihua Wang, Yixia Qian, Yunhong Jia, Weizhi Wang, Zhiyuan Hu*
    Biomater. Sci. 2017, 5, 417-421.
  10. Switchable Liposomes: Targeting Peptides Functionalized and pH-Triggered Cytoplasmic Delivery
    Qiuju Han, Weizhi Wang, Xiangqian Jia, Yixia Qian, Qian Li, Zihua Wang, Weikai Zhang, Shu Yang, Yunhong Jia, Zhiyuan Hu*
    ACS Appl. Mater. Interfaces 2016, 8, (29), 18658-18663.
  11. Micromixer based Preparation of Functionalized Liposomes and Targeting Drug Delivery
    Xiangqian Jia, Weizhi Wang, Qiuju Han, Zihua Wang, Yunhong Jia, Zhiyuan Hu*
    ACS Med. Chem. Lett. 2016, 7, 429-434.
  12. Switchable Probes: pH-Triggered and VEGFR2 Targeted Peptides Screening through Imprinting Microarray
    Yixia Qian, Weizhi Wang, Zihua Wang, Qiuju Han, Xiangqian Jia, Shu Yanga, Zhiyuan Hu*
    Chem. Commun. 2016, 52, 5690-5693.
  13. Peptide Functionalized Targeting Liposomes: for Nanoscale Drug Delivery towards Angiogenesis
    Qiuju Han, Xiangqian Jia, Yixia Qian, Zihua Wang, Shu Yang, Yunhong Jia,Weizhi Wang, Zhiyuan Hu*
    J. Mater. Chem. B, 2016, 4, 7087-7091
  14. Peptide-Conjugated PEGylated PAMAM as a High Affinitive Nanocarrier towards HER2-overexpressing Cancer Cells
    Iman Rostami, Zijian Zhao, Zihua Wang, Weikai Zhang, Yeteng Zhong, Qiang Zeng, Xinru Jia*, Zhiyuan Hu*
    RSC Adv. 2016, 6, 107337-107343
  15. HER2 Targeting Peptides Screening and Applications in Tumor Imaging and Drug Delivery Lingling Geng, Zihua Wang, Xiangqian Jia, Qiuju Han, Zhichu Xiang, Dan Li, Xiaoliang Yang, Di Zhang, Xiangli Bu, Weizhi Wang, Zhiyuan Hu*, Qiaojun Fang*
    Theranostics 2016, 6(8), 1261-1273
  16. Microarray Based Screening of Peptide Nano Probes for HER2 Positive Tumor
    Zihua Wang, Weizhi Wang, Xiangli Bu, Zewen Wei, Lingling Geng, Yue Wu, Chengyan Dong,
    Liqiang Li, Di Zhang, Shu Yang, Fan Wang, Christopher Lausted, Leroy Hood, Zhiyuan Hu*
    Anal. Chem. 2015, 87, 8367-8372
  17. Distinguishing of Tumor Cell-targeting Peptide ligands through a Color-encoding Microarray
    Zihua Wang, Weizhi Wang, Lingling Geng, Zhiyuan Hu*
    Lab Chip 2015, 15, 4512-4516
  18. Discovering of Tumor-targeting Peptides using Bi-functional Microarray
    Weizhi Wang, Zihua Wang, Xiangli Bu, Ren Li, Mingxing Zhou, Zhiyuan Hu*
    Adv. Healthc. Mater. 2015, 4, 2802-2808
  19. Structure-based Design of Peptides with High Affinity and Specificity to HER2 Positive Tumors
    Lingling Geng, Zihua Wang, Xiaoliang Yang, Dan Li, Wenxi Lian, Zhichu Xiang, Weizhi Wang, Xiangli Bu,Wenjia Lai, Zhiyuan Hu*, Qiaojun Fang*
    Theranostics 2015, 5(10), 1154-1165
  20. Energy Migration Engineering of Bright Rare-Earth Upconversion Nanoparticles for Excitation by Light Emitting Diodes
    Yeteng Zhong, Iman Rostami, Zihua Wang, Hongjie Dai*, Zhiyuan Hu*
    Adv. Mater., 2015, 27, 6418-6422
  21. Label-free detection Microarray for novel Peptide ligands Screening base on MS-SPRi combination
    Weizhi Wang, Di Zhang, Zewen Wei, Zihua Wang, Xiangli Bu, Shu Yang, Qiaojun Fang, Zhiyuan Hu*
    Talanta 2015, (134) 705-711
  22. A Continuous Flow Micro?uidic-MS system for e?cient OBOC Screening
    Weizhi Wang, Zewen Wei, Zihua Wang, Huailei Ma, Xiangli Bu, Zhiyuan Hu*
    RSC Adv. 2014, 4, 61767-61770
  23. Bimodal Imprint Chips for Peptide Screening: Integration of High-Throughput Sequencing by MS and A?nity Analyses by Surface Plasmon Resonance Imaging
    Weizhi Wang, Menglin Li, Zewen Wei, Zihua Wang, Xiangli Bu, Wenjia Lai, Shu Yang, He Gong, Hui Zheng, Yuqiao Wang, Ying Liu, Qin Li, Qiaojun Fang, Zhiyuan Hu*
    Anal. Chem. 2014, 86, 3703-3707
  24. Rapid Screening of Peptide Probes through In Situ Single-Bead Sequencing Microarray
    Weizhi Wang, Zewen Wei, Di Zhang, Huailei Ma, Zihua Wang, Xiangli Bu, Menglin Li, Lingling Geng, Christopher Lausted, Leroy Hood, Qiaojun Fang, Hao Wang, Zhiyuan Hu*??
    Anal. Chem. 2014, 86, 11854-11859
  25. An automated Teflon Microfluidic Peptide Synthesizer
    Hui Zheng, Weizhi Wang, Xiaojun Li, Zihua Wang, Leroy Hood, Christopher Lausted, Zhiyuan Hu*
    Lab Chip 2013, 13, 3347-3350
 
         Patent  
 
               Back