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	Institute of Chemistry, Chinese Academy of Sciences, Bei Yi Jie 2, Zhong Guan Cun, 100190, Beijing Tel: (010) 82613216, 62625212; Email: houyi[at]iccas.ac.cn

Research
		Yi Hou joined Prof. Mingyuan Gao's group in July 2011, and his major research focuses on synthesis and bioapplications of functional nanomaterials.

Curriculum Vitae
		Dec 1981 born in Neimenggu Province
		2000-2004 Bachelor degree, Chemical Physics, Department of Chemical Physics, University of Science and Technology of China
		2004-2009 Ph.D., Chemical Physics, Department of Chemical Physics, University of Science and Technology of China
		2010-2011 Postdoctoral fellow, University of Toronto, advisor: Professor Mitchell. A.Winnik
		July, 2011 Assistant Professor, Institute of Chemistry, CAS
		June, 2013 Associate Professor, Institute of Chemistry, CAS

Publications
	Upconversion Luminescence Mediated Photodynamic Therapy through Hydrophilically Engineered Porphyrin Xiaodan Sun^‡, Peisen Zhang^‡, Yi Hou, Yingying Li, Xiaodan Huang, Zihua Wang, Lihong Jing, and Mingyuan Gao* Chem. Eng. Process., 2019, just accepted. Coordinatively Unsaturated Fe³⁺ Based Activable Probes for Enhanced MRI and Therapy of Tumors Peisen Zhang, Yi Hou, Jianfeng Zeng, Yingying Li, Zihua Wang, Ran Zhu, Tiancong Ma, and Mingyuan Gao Angew. Chem. Int. Ed., 2019, DOI: 10.1002/anie.201904880. ‘Smart’ Nanoprobes for Visualization of Tumor Microenvironment Tiancong Ma, Peisen Zhang, Yi Hou, Haoran Ning, Zihua Wang, Jiayi Huang, and Mingyuan Gao Adv. Health. Mater., 2018, accepted. Timely Visualization of the Collaterals Formed during Acute Ischemic Stroke with Fe₃O₄ Nanoparticle-based MR Imaging Probe* Ting Wang, Yi Hou, Bo Bu, Wenxin Wang, Tiancong Ma, Chunyan Liu, Lan Lin, Lin Ma, Xin Lou,* and Mingyuan Gao Small, 2018, 14, 1800573. Molecular Mechanisms for Delicately Tuning the Morphology and Property of Fe₃O₄ Nanoparticle Clusters Xiaojun Wei, Lihong Jing, Chuanyan Liu, Yi Hou, Mingxia Jiao, and Mingyuan Gao* CrystEngComm, 2018, just accepted. A Novel Histochemical Staining Approach for Rare-Earth Based Nanoprobes Jiayi Huang, Yi Hou, Tiancong Ma, Peisen Zhang, Yingying Li, Chunyan Liu, Boyuan Zhang, Shanshan Qiu, Jianfeng Zeng, and Mingyuan Gao Adv. Therap., 2018, just accepted. Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in vivo Tiancong Ma^‡, Yi Hou^‡, Jianfeng Zeng^‡, Chunyan Liu, Peisen Zhang, Lihong Jing, Dihua Shangguan, and Mingyuan Gao* J. Am. Chem. Soc., 2017, DOI: 10.1021/jacs.7b08900. Biodegradable Nano-agents with Short Biological Half-life for SPECT/PAI/MRI Multimodality Imaging and PTT Therapy of Tumors Lei Chen, Jaiyao Chen, Shanshan Qiu, Ling Wen, Yan Wu, Yi Hou, Yong Wang, Jianfeng Zeng, Yuan Feng, Zhen Li, Hong Shan, and Mingyuan Gao* Small, 2017, just accepted Tumor Microenvironment-Triggered Aggregation of Anti-Phagocytosis ^99mTc-Labelled Fe₃O₄ Nanoprobes for Enhanced Tumor Imaging in Vivo Zhenyu Gao^‡, Yi Hou^‡, Jianfeng Zeng, Lei Chen, Chunyan Liu, Wensheng Yang, and Mingyuan Gao Adv. Mater., 2017, 29(24), 1701095 Graphene Oxide-based Sensor for Ultrasensitive Visual Detection of Fluoride Tapas K. Manda^‡, Yi Hou^‡, Zhenyu Gao, Haoran Ning, Wensheng Yang, and Mingyuan Gao* Adv. Sci., 2016, DOI: 10.1002/advs.201600217. Differently Sized Magnetic/Upconversion Luminescent NaGdF₄:Yb,Er Nanocrystals: Flow Synthesis and Solvent Effects Mingxia Jiao, Lihong Jing, Chunyan Liu, Yi Hou, Jiayi Huang, Xiaojun Wei, and Mingyuan Gao* Chem. Commun., 2016, 52(34), 5872-5875. Generation, Characterization, and Application of Hierarchically Structured Self-assembly Induced by the Combined Effect of Self-emulsification and Phase Separation Xiuyu Wang, Yi Hou, Li Yao, Mingyuan Gao, Maofa Ge J. Am. Chem. Soc., 2016, 138(7), 2090–2093. Detection of Early Primary Colorectal Cancer with Upconversion Luminescence NPs‐Based Molecular Probes Chunyan Liu^‡, Yifei Qi^‡, Ruirui Qiao, Yi hou, Kaying Chan, Ziqian Li, Jiayi Huang, Lihong Jing, Jun Du, and Mingyuan Gao Nanoscale, 2016, DOI: 10.1039/C5NR07858J. Chemical Spacer Design for Engineering the Relaxometric Properties of Core-Shell Structured Rare Earth Nanoparticles Jiayi Huang, Yi Hou, Chunyan Liu, Lihong Jing, Tiancong Ma, Xiaodan Sun, and Mingyuan Gao Chem. Mater., 2015, 27(23), 7918-7925. Super-stable Centimetre-scale Inverse Opal Belts Integrated with CdTe QDs for Narrow Band Fluorescence Optical Waveguiding Xianyong Lu, Lingmei Nia, Shimin Wu, Yanzi Wu, Hongyan Cai, Ke Ding, Lihong Jing, Yi Hou, Ying Zhu, Mingyuan Gao, and Lei Jiang J. Mater. Chem. C, 2015, DOI: 10.1039/C5TC02568K. Protease-Activated Ratiometric Fluorescent Probe for pH Mapping of Malignant Tumors Yi Hou, Jin Zhou, Zhenyu Gao, Xiaoyu Sun, Chunyan Liu, Dihua Shangguan, Wensheng Yang, and Mingyuan Gao* ACS Nano, 2015, 9(3), 3199–3205. Ultrasensitive in Vivo Detection of Primary Gastric Tumor and Lymphatic Metastasis Using Upconversion Nanoparticles Ruirui Qiao, Changhao Liu, Muhan Liu, Hao Hu, Chunyan Liu, Yi Hou, Kaichun Wu, Yenan Lin, Jimin Liang, Mingyuan Gao ACS Nano, 2015, accepted. Upconversion Luminescence Nanoparticles-Based Lateral Flow Immunochromatographic Assay for Cephalexin Detection Chunyan Liu, Wei Ma, Zhenyu Gao, Jiayi Huang, Yi Hou, Chuanlai Xu, Wensheng Yang, and Mingyuan Gao* J. Mater. Chem. C, 2014, 2(45), 9637-9642. Restructuring and Remodeling of NaREF₄ Nanocrystals by Electron Irradiation Xiaoyu Sun^‡, Bingru Wang^‡, Ivan M. Kempson^‡, Chunyan Liu, Yi Hou,* and Mingyuan Gao* Small, 2014, accepted. Revisiting the Coordination Chemistry for Preparing Manganese Oxide Nanocrystals in the Presence of Oleylamine and Oleic Acid Hongwei Zhang, Lihong Jing, Jianfeng Zeng, Yi Hou, Zhen Li,* and Mingyuan Gao* Nanoscale, 2014, 6(11), 5918-5925. Are Rare-Earth Nanoparticles Suitable for In Vivo Applications? Chunyan Liu, Yi Hou, and Mingyuan Gao* Adv. Mater., 2014, 26(17), 2694-2698. Anchoring Group Effects of Surface Ligand on Magnetic Properties of Fe₃O₄ Nanoparticles: Towards High Performance MRI Contrast Agents Jianfeng Zeng, Lihong Jing, Yi Hou, Mingxia Jiao, Ruirui Qiao, Qiaojuan Jia, Chunyan Liu, Fang Fang, Hao Lei, and Mingyuan Gao* Adv. Mater., 2014, DOI: 10.1002/adma.201304744. Magnetically Engineered Cd-Free Quantum Dots as Dual-modality Probes for Fluorescence/Magnetic Resonance Imaging of Tumors Ke Ding, Lihong Jing, Chunyan Liu, Yi Hou, and Mingyuan Gao Biomaterials, 2014, 35(5), 1608-1617. Bifunctional Superparticles Achieved by Assembling Fluorescent CuInS₂@ZnS Quantum Dots and Amphibious Fe₃O₄ Nanocrystals Xiaoyu Sun, Ke Ding, Yi Hou , Zhenyu Gao, Wensheng Yang, Lihong Jing, and Mingyuan Gao* J. Phys. Chem. C, 2013, 117(40), 21014–21020. Magnetic/Upconversion Fluorescent NaGdF₄:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo Chunyan Liu, Zhenyu Gao, Jianfeng Zeng, Yi Hou, Fang Fang, Yilin Li, Ruirui Qiao, Lin Shen, Hao Lei, Wensheng Yang, and Mingyuan Gao ACS Nano, 2013, 7(8), 7227-7240. NaGdF ₄ Nanoparticle-Based Molecular Probes for Magnetic Resonance Imaging of Intraperitoneal Tumor Xenografts In Vivo Yi Hou, Ruirui Qiao, Fang Fang, Xuxia Wang, Chengyan Dong, Kan Liu, Chunyan Liu, Zhaofei Liu, Hao Lei, Fan Wang, and Mingyuan Gao ACS Nano, 2013, 7(1), 330-338. Reentrant Behavior of Grafted Poly(sodium styrenesulfonate) Chains Investigated with a Quartz Crystal Microbalance Yi Hou, Ying Wu, Guangming Liu, Guangzhao Zhang Phys. Chem. Chem. Phys. 2011, 13, 2880-2886. Effects of Anions on the Aggregation Charged Microgels Yi Hou, Changqian Yu, Guangming Liu, To Ngai, Guangzhao Zhang J. Phys. Chem. B 2010, 114, 3799-3803. Effects of Cations on the Sorting of Oppositely Charged Microgels Yi Hou, Jing Ye, Xiaoling Wei, Guangzhao Zhang J. Phys. Chem. B 2009, 113, 7457-7461. Temperature-Modulated Photoluminescence of Quantum Dots Yi Hou, Jing Ye, Zhou Gui, Guangzhao Zhang Langmuir 2008, 24, 9682-9685. In situ Investigations on Enzymatic Degradation of Poly(ε-caprolactone) Yi Hou, Jing Chen, Peijian Sun, Zhihua Gan Guangzhao Zhang Polymer 2007, 48, 6348-6353. Specific Anion Effects on the Growth of a Polyelectrolyte Multilayer in Single and Mixed Electrolyte Solutions Investigated with Quartz Crystal Microbalance Guangming Liu, Yi Hou, Xiao Xiao, Guangzhao Zhang J. Phys. Chem. B 2010, 114, 9987-9993. pH Induced DNA Folding at Interface Hongwei Xia, Yi Hou, To Ngai, Guangzhao Zhang J. Phys. Chem. B 2010, 114, 775-779. Effect of Microphase Separation on the Protein Resistance of a Polymeric Surface Chunfeng Ma, Yi Hou, Shi Liu, Guangzhao Zhang Langmuir 2009, 25, 9467-9472. Inhibition of Bubble Coalescence by Electrolytes in Binary Mixtures of Dimethyl Sulfoxide and Propylene Carbonate Guangming Liu, Yi Hou, Guangzhao Zhang, Vincent S. J. Craig Langmuir 2009, 25, 10495-10500. Temperature-Induced Aggregation of Poly(N-isopropylacrylamide)-Stabilized CdS Quantum Dots in Water Guangming Liu, Yi Hou, Guangzhao Zhang, Vincent S. J. Craig Langmuir 2008, 24, 2727-2731. Influence of chemical structure on enzymatic degradation of single crystal of PCL-b-PEO amphiphilic block copolymer Ni Jiang, Shidong Jiang, Yi Hou, Shouke Yan, Guangzhao Zhang, Zhihua Gan Polymer 2010, 51, 2426-2434. Viscoelastic Properties of Polyethylene Glycol (PEG) Boundary Layers near a Solid Substrate Ping Wang, Jiajie Fang, Yi Hou, Xianbin Du, Daming Zhu J. Phys. Chem. C 2009, 113, 729-735. Multiresponsive Surfaces Change between Superhydrophilicity and Superhydrophobicity Fan Xia, Hui Ge, Yi Hou, Taolei Sun, Li Chen, Guangzhao Zhang, Lei Jiang Adv. Mater. 2007, 19, 2520-2524. Adsorption Isotherms and Dissipation of Adsorbed Poly(N-isopropylacrylamide) in Its Swelling and Collapsed States Kun Wu, Bing Wu, Ping Wang, Yi Hou, Guangzhao Zhang, Daming Zhu J. Phys. Chem. B 2007, 111, 8723-8727.
Patents

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