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王广林 |
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王广林,硕士生导师、副教授 |
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先后主持国家重点研发专项项目子课题1项,基金委材料学部青年基金1相,基金委化学部面上项目1项,江苏省自然科学基金青年和优秀青年基金项目各1项。安徽省自然科学基金面上项目1项。2016年获苏州市高层次紧缺人才。2013年和2017年两次获得International Symposium on Targeted Alpha Therapy的Travel Award。截止目前,在ACS Appl. Mater. Interfaces, Biomaterials Science等学术期刊上共发表学术论文20篇。 | ||||
个人简历 | ||||
2009-2014年 | 荷兰代尔夫特理工大学,反应堆研究所,博士,导师:H. Th. Wolterbeek教授 | |||
2006-2009年 | 中国科学技术大学,同步辐射国家实验室,硕士,导师:李良彬教授 | |||
2001-2005年 | 安徽大学,高分子材料与工程系,本科 | |||
研究方向 | ||||
放射性核素标记方法的研究 | ||||
放射性核素标记用于药物药代动力学研究 | ||||
放射性标记药物在肿瘤诊断和治疗中的应用研究 | ||||
代表性论文 | ||||
1. Acidity-Activated Charge Conversion of 177Lu-Labeled Nanoagent for the Enhanced Photodynamic Radionuclide Therapy of Cancer Yuan Zhang#, Guanglin Wang#, Qing Li*, Yue Jiang, Wan Chen, Min Zhao, Gaolin Liang, Qingqing Miao* ACS Appl. Mater. Interfaces, 2022, 14 (3), 3875-3884. 2. Facile Preparation of 177Lu-microspheres for Hepatocellular Carcinoma Radioisotope Therapy Manran Wu, Kexin Shi, Ruizhe Huang, Chunyi Liu, Lingling Yin, Weipeng Yong, Jing Sun, Guanglin Wang*, and Mingyuan Gao* Chinese Chemical Letter, 2022, 33, 3492-3496. 3. Redox-sensitive iodinated polymersomes carrying histone deacetylase inhibitor as a dual-functional nano-radiosensitizer for enhanced radiotherapy of breast cancer Zhehong Zhu, Manran Wu, Juan Sun, Zhengyuan Huangfu, Lingling Yin, Weipeng Yong, Jing Sun, Guanglin Wang*, Fenghua Meng, Zhiyuan Zhong* Drug Delivery, 2021, 28, 2301-2309. 4. Sequential SPECT and NIR-II imaging of tumor and sentinel lymph node metastasis for diagnosis and image-guided surgery Xiaolu Zhang#, Meng Zhao#, Ling Wen#, Manran Wu, Yi Yang, Yujuan Zhang, Yan Wu, Jian Zhong*, Haibin Shi, Jianfeng Zeng, Guanglin Wang*, Mingyuan Gao* Biomaterials Science, 2021, 9, 3069. 5. Iodine-rich Polymersomes Enable Versatile SPECT/CT Imaging and Potent Radioisotope Therapy for Tumor In Vivo Jinsong Cao, Yaohua Wei, Yanxiang Zhang, Guanglin Wang*, Xiang Ji, and Zhiyuan Zhong* ACS Appl. Mater. Interfaces, 2019, 11, 18953-18959. 6. Rhenium-188 Labeled Tungsten Disulfide Nanoflakes for Self-sensitized, Near-infrared Enhanced Radioisotope Therapy Yu Chao, Guanglin Wang, Chao Liang, Xuan Yi, Xiaoyan Zhong, Jingjing Liu, Min Gao, Kai Yang*, Liang Cheng*, and Zhuang Liu* Small, 2016, 12, 3967-3975. 7. Pharmacokinetics of Polymersomes Composed of Poly(butadiene-ethylene oxide); Healthy vs. Tumor Bearing Mice Guanglin Wang, R. M. de Kruijff, D. Abou, N. Ramos, E. Mendes, L. E. Franken, H. T. Wolterbeek, and A. G. Denkova* J. Biomed. Nano., 2016, 12, 320-328. 8. Enhanced Retention of Encapsulated Ions in Cross-Linked Polymersomes Guanglin Wang, A. Hoornweg, H Th. Wolterbeek, L. Franken, E. Mendes, and A. G. Denkova* J. Phys. Chem. B, 2015, 119(11), 4300-4308. 9. Retention Studies of Recoiling Daughter Nuclides of 225Ac in Polymer Vesicles Guanglin Wang, R.M. de Kruijff, A. Rol, L. Thijssen, E. Mendes, A. Morgenstern, F. Bruchertseifer, M.C.A. Stuart, H.Th. Wolterbeek, and A.G. Denkova* Appl. Radiat. Isotopes, 2014, 85, 45-53. 10. Polymersomes as Radionuclide Carriers Loaded via Active Ion Transport through the Hydrophobic Bilayer Guanglin Wang, R. de Kruijff, M. C. A. Stuart, E. Mendes, H. T. Wolterbeek, and A. G. Denkova* Soft Matter, 2013, 9, 727. |
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