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    侯毅  
 
       
 
         研究方向  
      2011年7月被引进到中科院化学研究所工作,主要从事功能纳米材料的制备及其生物应用研究。  
 
         个人简历  
      1981年12月  出生于内蒙古包头市  
      1997-2000    内蒙古包头市第九中学(高中)  
      2000-2004    中国科技大学物理系攻读学士学位(本科)  
      2004-2009    中国科技大学物理系(博士)  
      2010-2011    加拿大多伦多大学化学系,博士后,合作导师:Prof. Mitchell. A.Winnik
 
      2011年7月   中国科学院化学研究所,助理研究员  
      2013-2019   中国科学院化学研究所,副研究员  
      2019年7月    现就职于北京化工大学,副教授  
 
         发表论文  
   
  1. Emitting/Sensitizing Ions Spatially Separated Lanthanide Nanocrystals for Visualizing Tumors Simultaneously through Up- and Down-conversion Near-infrared II Luminescence in Vivo
    Yingying Li, Peisen Zhang, Haoran Ning, Jianfeng Zeng, Yi Hou, Lihong Jing, Chunyan Liu, Mingyuan Gao*
    Small, 2019, just accepted.
  2. Upconversion Luminescence Mediated Photodynamic Therapy through Hydrophilically Engineered Porphyrin
    Xiaodan Sun, Peisen Zhang, Yi Hou*, Yingying Li, Xiaodan Huang, Zihua Wang, Lihong Jing*, and Mingyuan Gao*
    Chem. Eng. Process., 2019, just accepted.
  3. Coordinatively Unsaturated Fe3+ Based Activable Probes for Enhanced MRI and Therapy of Tumors
    Peisen Zhang, Yi Hou*, Jianfeng Zeng, Yingying Li, Zihua Wang, Ran Zhu, Tiancong Ma, and Mingyuan Gao*
    Angew. Chem. Int. Ed., 2019, DOI: 10.1002/anie.201904880.
  4. ‘Smart’ Nanoprobes for Visualization of Tumor Microenvironment
    Tiancong Ma, Peisen Zhang, Yi Hou*, Haoran Ning, Zihua Wang, Jiayi Huang, and Mingyuan Gao
    Adv. Health. Mater., 2018, accepted.
  5. Timely Visualization of the Collaterals Formed during Acute Ischemic Stroke with Fe3O4 Nanoparticle-based MR Imaging Probe
    Ting Wang, Yi Hou, Bo Bu, Wenxin Wang, Tiancong Ma, Chunyan Liu, Lan Lin, Lin Ma, Xin Lou,* and Mingyuan Gao
    Small, 2018, 14, 1800573.
  6. Molecular Mechanisms for Delicately Tuning the Morphology and Property of Fe3O4 Nanoparticle Clusters
    Xiaojun Wei, Lihong Jing, Chuanyan Liu, Yi Hou, Mingxia Jiao, and Mingyuan Gao*
    CrystEngComm, 2018, just accepted.
  7. A Novel Histochemical Staining Approach for Rare-Earth Based Nanoprobes
    Jiayi Huang, Yi Hou*, Tiancong Ma, Peisen Zhang, Yingying Li, Chunyan Liu, Boyuan Zhang, Shanshan Qiu, Jianfeng Zeng, and Mingyuan Gao*
    Adv. Therap., 2018, just accepted.
  8. Dual-Ratiometric Target-Triggered Fluorescent Probe for Simultaneous Quantitative Visualization of Tumor Microenvironment Protease Activity and pH in vivo
    Tiancong Ma, Yi Hou, Jianfeng Zeng, Chunyan Liu, Peisen Zhang, Lihong Jing, Dihua Shangguan, and Mingyuan Gao*
    J. Am. Chem. Soc., 2018, 140(1), 211–218.
  9. Biodegradable Nano-agents with Short Biological Half-life for SPECT/PAI/MRI Multimodality Imaging and PTT Therapy of Tumors
    Lei Chen, Jaiyao Chen, Shanshan Qiu, Ling Wen, Yan Wu, Yi Hou, Yong Wang, Jianfeng Zeng*, Yuan Feng, Zhen Li, Hong Shan*, and Mingyuan Gao*
    Small, 2017, just accepted
  10. Tumor Microenvironment-Triggered Aggregation of Anti-Phagocytosis 99mTc-Labelled Fe3O4 Nanoprobes for Enhanced Tumor Imaging in Vivo
    Zhenyu Gao, Yi Hou, Jianfeng Zeng, Lei Chen, Chunyan Liu, Wensheng Yang*, and Mingyuan Gao*
    Adv. Mater., 2017, 29(24), 1701095
  11. Graphene Oxide-based Sensor for Ultrasensitive Visual Detection of Fluoride
    Tapas K. Manda, Yi Hou, Zhenyu Gao, Haoran Ning, Wensheng Yang, and Mingyuan Gao*
    Adv. Sci., 2016, DOI: 10.1002/advs.201600217.
  12. Differently Sized Magnetic/Upconversion Luminescent NaGdF4:Yb,Er Nanocrystals: Flow Synthesis and Solvent Effects
    Mingxia Jiao, Lihong Jing, Chunyan Liu, Yi Hou, Jiayi Huang, Xiaojun Wei, and Mingyuan Gao*
    Chem. Commun., 2016, 52(34), 5872-5875.
  13. Generation, Characterization, and Application of Hierarchically Structured Self-assembly Induced by the Combined Effect of Self-emulsification and Phase Separation
    Xiuyu Wang, Yi Hou, Li Yao*, Mingyuan Gao*, Maofa Ge
    J. Am. Chem. Soc., 2016, 138(7), 2090–2093.
  14. Detection of Early Primary Colorectal Cancer with Upconversion Luminescence NPs‐Based Molecular Probes
    Chunyan Liu, Yifei Qi, Ruirui Qiao, Yi hou, Kaying Chan, Ziqian Li, Jiayi Huang, Lihong Jing, Jun Du*, and Mingyuan Gao*
    Nanoscale, 2016, DOI: 10.1039/C5NR07858J.
  15. Chemical Spacer Design for Engineering the Relaxometric Properties of Core-Shell Structured Rare Earth Nanoparticles
    Jiayi Huang, Yi Hou, Chunyan Liu*, Lihong Jing, Tiancong Ma, Xiaodan Sun, and Mingyuan Gao*
    Chem. Mater., 2015, 27(23), 7918-7925.
  16. Super-stable Centimetre-scale Inverse Opal Belts Integrated with CdTe QDs for Narrow Band Fluorescence Optical Waveguiding
    Xianyong Lu*, Lingmei Nia, Shimin Wu, Yanzi Wu, Hongyan Cai, Ke Ding, Lihong Jing, Yi Hou, Ying Zhu*, Mingyuan Gao, and Lei Jiang
    J. Mater. Chem. C, 2015, DOI: 10.1039/C5TC02568K.
  17. Protease-Activated Ratiometric Fluorescent Probe for pH Mapping of Malignant Tumors
    Yi Hou, Jin Zhou, Zhenyu Gao, Xiaoyu Sun, Chunyan Liu, Dihua Shangguan, Wensheng Yang, and Mingyuan Gao*
    ACS Nano, 2015, 9(3), 3199–3205.
  18. Ultrasensitive in Vivo Detection of Primary Gastric Tumor and Lymphatic Metastasis Using Upconversion Nanoparticles
    Ruirui Qiao, Changhao Liu, Muhan Liu, Hao Hu, Chunyan Liu, Yi Hou, Kaichun Wu*, Yenan Lin, Jimin Liang, Mingyuan Gao*
    ACS Nano, 2015, accepted.
  19. Upconversion Luminescence Nanoparticles-Based Lateral Flow Immunochromatographic Assay for Cephalexin Detection
    Chunyan Liu, Wei Ma, Zhenyu Gao, Jiayi Huang, Yi Hou, Chuanlai Xu, Wensheng Yang, and Mingyuan Gao*
    J. Mater. Chem. C, 2014, 2(45), 9637-9642.
  20. Restructuring and Remodeling of NaREF4 Nanocrystals by Electron Irradiation
    Xiaoyu Sun, Bingru Wang, Ivan M. Kempson, Chunyan Liu, Yi Hou,* and Mingyuan Gao*
    Small, 2014, accepted.
  21. Revisiting the Coordination Chemistry for Preparing Manganese Oxide Nanocrystals in the Presence of Oleylamine and Oleic Acid
    Hongwei Zhang, Lihong Jing, Jianfeng Zeng, Yi Hou, Zhen Li,* and Mingyuan Gao*
    Nanoscale, 2014, 6(11), 5918-5925.
  22. Are Rare-Earth Nanoparticles Suitable for In Vivo Applications?
    Chunyan Liu, Yi Hou, and Mingyuan Gao*
    Adv. Mater., 2014, DOI: 10.1002/adma.201305535 .
  23. Anchoring Group Effects of Surface Ligand on Magnetic Properties of Fe3O4 Nanoparticles: Towards High Performance MRI Contrast Agents
    Jianfeng Zeng, Lihong Jing, Yi Hou, Mingxia Jiao, Ruirui Qiao, Qiaojuan Jia, Chunyan Liu, Fang Fang, Hao Lei, and Mingyuan Gao*
    Adv. Mater., 2014, 26(17), 2694-2698.
  24. Magnetically Engineered Cd-Free Quantum Dots as Dual-modality Probes for Fluorescence/Magnetic Resonance Imaging of Tumors
    Ke Ding, Lihong Jing*, Chunyan Liu, Yi Hou, and Mingyuan Gao*
    Biomaterials, 2014, 35(5), 1608-1617.
  25. Bifunctional Superparticles Achieved by Assembling Fluorescent CuInS2@ZnS Quantum Dots and Amphibious Fe3O4 Nanocrystals
    Xiaoyu Sun, Ke Ding, Yi Hou , Zhenyu Gao, Wensheng Yang, Lihong Jing, and Mingyuan Gao*
    J. Phys. Chem. C, 2013, 117(40), 21014–21020.
  26. Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo
    Chunyan Liu, Zhenyu Gao, Jianfeng Zeng, Yi Hou*, Fang Fang, Yilin Li, Ruirui Qiao, Lin Shen, Hao Lei, Wensheng Yang, and Mingyuan Gao*
    ACS Nano, 2013, 7(8), 7227-7240.
  27. NaGdF4 Nanoparticle-Based Molecular Probes for Magnetic Resonance Imaging of Intraperitoneal Tumor Xenografts In Vivo
    Yi Hou, Ruirui Qiao, Fang Fang, Xuxia Wang, Chengyan Dong, Kan Liu, Chunyan Liu, Zhaofei Liu, Hao Lei*, Fan Wang, and Mingyuan Gao*
    ACS Nano, 2013, 7(1), 330-338.
  28. Reentrant Behavior of Grafted Poly(sodium styrenesulfonate) Chains Investigated with a Quartz Crystal Microbalance
    Yi Hou, Ying Wu, Guangming Liu, Guangzhao Zhang
    Phys. Chem. Chem. Phys. 2011, 13, 2880-2886.
  29. Effects of Anions on the Aggregation Charged Microgels
    Yi Hou, Changqian Yu, Guangming Liu, To Ngai, Guangzhao Zhang
    J. Phys. Chem. B 2010, 114, 3799-3803.
  30. Effects of Cations on the Sorting of Oppositely Charged Microgels
    Yi Hou, Jing Ye, Xiaoling Wei, Guangzhao Zhang
    J. Phys. Chem. B 2009, 113, 7457-7461.
  31. Temperature-Modulated Photoluminescence of Quantum Dots
    Yi Hou, Jing Ye, Zhou Gui, Guangzhao Zhang
    Langmuir 2008, 24, 9682-9685.
  32. In situ Investigations on Enzymatic Degradation of Poly(ε-caprolactone)
    Yi Hou, Jing Chen, Peijian Sun, Zhihua Gan Guangzhao Zhang
    Polymer 2007, 48, 6348-6353.
  33. Specific Anion Effects on the Growth of a Polyelectrolyte Multilayer in Single and Mixed Electrolyte Solutions Investigated with Quartz Crystal Microbalance
    Guangming Liu, Yi Hou, Xiao Xiao, Guangzhao Zhang
    J. Phys. Chem. B 2010, 114, 9987-9993.
  34. pH Induced DNA Folding at Interface
    Hongwei Xia, Yi Hou, To Ngai, Guangzhao Zhang
    J. Phys. Chem. B 2010, 114, 775-779.
  35. Effect of Microphase Separation on the Protein Resistance of a Polymeric Surface
    Chunfeng Ma, Yi Hou, Shi Liu, Guangzhao Zhang
    Langmuir 2009, 25, 9467-9472.
  36. Inhibition of Bubble Coalescence by Electrolytes in Binary Mixtures of Dimethyl Sulfoxide and Propylene Carbonate
    Guangming Liu, Yi Hou, Guangzhao Zhang, Vincent S. J. Craig
    Langmuir 2009, 25, 10495-10500.
  37. Temperature-Induced Aggregation of Poly(N-isopropylacrylamide)-Stabilized CdS Quantum Dots in Water
    Guangming Liu, Yi Hou, Guangzhao Zhang, Vincent S. J. Craig
    Langmuir 2008, 24, 2727-2731.
  38. Influence of chemical structure on enzymatic degradation of single crystal of PCL-b-PEO amphiphilic block copolymer
    Ni Jiang, Shidong Jiang, Yi Hou, Shouke Yan, Guangzhao Zhang, Zhihua Gan
    Polymer 2010, 51, 2426-2434.
  39. Viscoelastic Properties of Polyethylene Glycol (PEG) Boundary Layers near a Solid Substrate
    Ping Wang, Jiajie Fang, Yi Hou, Xianbin Du, Daming Zhu
    J. Phys. Chem. C 2009, 113, 729-735.
  40. Multiresponsive Surfaces Change between Superhydrophilicity and Superhydrophobicity
    Fan Xia, Hui Ge, Yi Hou, Taolei Sun, Li Chen, Guangzhao Zhang, Lei Jiang
    Adv. Mater. 2007, 19, 2520-2524.
  41. Adsorption Isotherms and Dissipation of Adsorbed Poly(N-isopropylacrylamide) in Its Swelling and Collapsed States
    Kun Wu, Bing Wu, Ping Wang, Yi Hou, Guangzhao Zhang, Daming Zhu
    J. Phys. Chem. B 2007, 111, 8723-8727.
 
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